44. Optimizing Human Health: Dr. Fady hannah-Shmouni on Personalized Medicine and Longevity
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Dr. Hannah-Schmouni (00:00)
I've retired from the traditional care models because I want to contribute towards a model that will prevent humans from reaching the disease states in the first place. But I have a lot of respect for what humans have built so far in the traditional care model. So in other words, I want to give a signal of hope and optimism that we're moving in the right direction for extending health span. The healthy years lived on earth.
And this is not magic and voodoo science. You we see it. know, rejuvenation is real. Aging is a choice. We can decelerate aging. We can create healthy, optimized humans. Today and in the near future, we're just going to double down on this potential. So I'm very bullish on where humanity is going to land in the near and far future.
Mizter Rad (00:56)
Welcome to the Mizter Rad Show, where I talk to the most interesting global personalities about the future of humanity.
Hello, beautiful humans. Today I'm diving into the future of healthcare, with someone who's transforming how we think about disease and aging. Our current medical system is failing us. We feel that, we know that, we wait until we are sick to see doctors, get generic treatments based on averages, average population, and focus on symptoms rather than prevention. My guest today is challenging this entire paradigm.
Dr. Fadi Hanna Schmouni is pioneering a healthcare revolution where medicine becomes proactive instead of reactive, personalized instead of standardized, and focused on optimizing your health rather than just treating disease. As an endocrinologist, he's uncovering the secrets of our body's hormone messenger. As a geneticist, he's using our DNA as a blueprint to predict health issues before they emerge.
And as the founder of several companies, he's building technologies that could add decades of healthy living to our lives. Dr. Hanna Schmoenig has authored over a hundred scientific publications and previously led groundbreaking research at the NIH. He is now at the forefront of a movement that could transform how long and how well we live. Dr. Schmoenig, welcome to the show. How are you doing, Fadi?
Dr. Hannah-Schmouni (02:41)
Hi Mr. Rad, I'm very, very good. Thanks so much for the kind introduction. I'm very happy to be with you today.
Mizter Rad (02:47)
Amazing it's a pleasure to have you here let's start by the fire make all your body with something very simple so most of us only go to the doctor when we're ready sick that's how we got raised. I need myself and i know the vast majority of my audience only go to the doctor when they're sick why do you think this approach is failing us and how. What should we be doing instead.
Dr. Hannah-Schmouni (03:13)
Yeah, you know, there's a big merit of having the existing traditional care model. I mean, we still save a lot of lives, treat many conditions in the traditional care model, but we have to understand that disease doesn't happen overnight, right? It's a continuum from a spectrum of wellness to a disease state, which takes sometimes decades to evolve through that spectrum. So the big question is when we redesign healthcare today, how can we view this spectrum?
as an opportunity to move the diagnostic threshold from the existing sick care model to more of sort of the earlier models of disease evolution so we can influence the trajectory of disease through the appropriate diagnosis and interventions, which will create an infliction point in someone's life and
overall for the entire population at large. So let's think about it as a spectrum and this new notion of proactive wellness, longevity-based models of care delivery are really meant to give an opportunity for the end consumer, everyone that's participating in this sort of newer economy to contribute to the health of the individual.
Mizter Rad (04:36)
But OK, so let me let me just step back a bit and before we dive deeper, I'm curious about your journey, because you were telling me that when I was looking into your profile, I understood that you went from a traditional, let's say, traditional institution like the NIH to pioneering this more personalized approach to health. What made you realize that the conventional approach was not working? Why did you take that step?
Dr. Hannah-Schmouni (05:05)
Yeah, great question. So I was always fascinated by the natural history of disease, how disease evolves over time from, you know, physiology state to a disease state, which takes, you know, number of years. And I've studied the spectrum and natural evolution of several diseases as a personal investigator at the National Institute of Health. So I was always fascinated by biomarkers and the evolution of disease and the natural history and course of disease.
And I was fortunate after leaving the NIH to have co-founded and invested in different wellness and longevity related companies on the consumer's product front and on the biotech and software front. And that opened my mind to the endless possibilities of how we can merge these very innovative products so we could provide better services and care delivery for populations at large. And that gave me the enthusiasm.
to continue to want to be involved in this space. The wellness and longevity economies projected to be 6 % of global GDP by 2030. That's about $10 trillion market value. So there's really a need for individuals to be thinking outside the box, to build products and services and the infrastructure and the rails needed to push this economy forward and to help with various healthcare models. The traditional care model is an important model that we have.
but there are other parallel models that are running with the traditional care model to provide that continuity of care.
Mizter Rad (06:34)
Okay, I see what you mean and I wanna touch that topic on sort of the future opportunities that this transformation of healthcare will bring for the future generations of business creators. But I wanna maybe challenge you on something here because when most people have health issues and they go to the doctor, they typically run some standard tests and compare those results to some general ranges. So if you go to measure your
vitamin D, whatever, and then when you get the results, you see the results and you're either within the range, the normal range or not. And then they give you standard treatments, of course, based on those standard measurements. Why is this one size fits all approach failing so many people?
Dr. Hannah-Schmouni (07:24)
Yeah, it's such a great question and we don't really know if it's truly failing people because we haven't really compared head to head for a very long time the proactive longevity wellness model and optimal reference ranges versus the population reference range traditional care model. So let's break it down. There's a merit in the traditional care system, right? If you're sick, especially with an acute illness, especially if it's life threatening.
you know, there's a big merit for being treated in the traditional care model. Having said that, the objective of these parallel healthcare delivery systems that are non-traditional is to actually prevent you from being a patient in the first place, right? We don't want you to be a patient. We want you to evolve from a healthy state to a diseased state in the first place. So now we're seeing a big push in this wellness and longevity economy, which is a massive economy and growing out an incredible CAGR.
to try to develop the rails, the diagnostics, the softwares, the products, the early disease intervention and diagnostics to prevent you from ultimately becoming a patient. Now, if you do become a patient because of bad luck, right? Because of whether it's genetics or exposures or chronic disease, then the wellness system is not gonna save you, right?
We've spent decades and a lot of money to develop these traditional care model protocols and they do work for most diseases. And I can name so many different diseases that as a product of the traditional care model, as a product of pharma and research and the FDA and the NIH and you name it, and the CDC, we're able to treat and potentially cure diseases through the traditional care model. Having said that, I've retired from the traditional care models because I want to
contribute towards a model that will prevent humans from reaching the disease state in the first place. I have a lot of respect for what humans have built so far in the traditional care model.
Mizter Rad (09:34)
And when you hear a lot of this longevity experts online, some of them trash a little bit the traditional medicine. And I think what you're saying is the opposite. What you're saying is let's respect what we've built so far because it has helped us a lot. Let's just not put it in the trash and then build on the side something that is complementary. Is it really complementary in the sense that
the big players on the traditional model are not gonna make as much money as they're doing now if you kind of saving people get healthier before they reach their practice.
Dr. Hannah-Schmouni (10:16)
Well, know, mister, there's good actors and bad actors in every sector and system, right? So there are good actors and bad actors in the traditional care system, and there are good actors and bad actors in the non-traditional care system, including the wellness and longevity economy. So what I'm saying is that there's an opportunity, right, in every system to generate value.
value for the end user, value for the consumer, value for the patient, to the clients. And I see value in the traditional care model, and I see bigger value in the wellness and longevity models that will run in parallel because disease is a continuum. And let's be realistic. All this big hopes about the wellness and longevity economy and model is not going to cure diseases.
diseases are here to stay. Our risk factors that contribute to the evolution of disease is not going to go away overnight, including environmental risk factors like the exposures we get from toxins and microplastics and all the gases in the air and the industrialization of our life. So disease is here to stay.
But with the technological advancements that we have today, we have an opportunity to move the curve from a higher threshold of diagnosis that leads to the traditional care model entry to a much lower threshold so we can intervene much earlier. And then to other potential threshold where you understand your risk through predictive algorithms, you understand your risk
And you can modify that risk through behavioral interventions to prevent you from going from that wellness model to the disease model. think about the newer types of healthcare as a hedge fund for your health. So hedge funds take on large data sets and predictive models, right, to predict stock performance or company performance. With our models today,
we can create the same hedge against our health, right? And if we hedge the right way, we can create a lot of magic to the trajectory of humans down the road.
Mizter Rad (12:44)
So, for health to prevent diseases, let's say. The best way we can.
Dr. Hannah-Schmouni (12:51)
Sure, I mean, that's one outcome, right? Is to prevent the evolution to chronic disease and premature death. The other potential outcome of this hedging, you know, with technology and predictive scores and early intervention is to actually optimize humans. And an optimized human will create a better output for themselves, for the families, for the economy. And amongst other positive outcomes that can come from
being healthy, including a better GDP and a much lower cost on healthcare and then the economy. And it creates a ripple effect on a lot of things down the road. So it's not just for health, but let's accept health. What is health? Health is everything around us, including the economy that we have. But it's building those rails and those algorithms and those diagnostic opportunities to optimize humans so they could live
healthier life and that's called healthspan, right, which is to optimize those last years that you live without disability and chronic disease. The goal is not longevity. The goal is to optimize you so you can live a happy long life and you can start that very early on through those opportunities we're discussing.
Mizter Rad (14:10)
Interesting, interesting. You touched the topic of human evolution and the environment and how we're constantly exposed to plastics, pesticides and chemicals. And while simultaneously we're gaining the ability to genes and manipulate hormones, in your case, probably you're a hormone expert, you can probably talk more about that, including those that enhance, for example, masculinity or femininity.
From your research and looking ahead, let's say 50 years from now, how might precision medicine and genetic interventions or hormonal interventions change the trajectory of human evolution? Do you think we'll be actively designing ourselves like you said, optimizing ourselves, our human bodies, let's say? And what do you think that might look like?
Dr. Hannah-Schmouni (15:04)
Yeah, Mr. is such a great question. So I don't know what, what the predictions are for 50 years down the road, but I could tell you the short-term predictions and some of the products that we currently have in the clinic. But today I have the ability to create induced pluripotent stem cells from your blood that I could store for 10 plus years. This is your biological insurance. I genetically engineered stem cells. So in the event that you want to regenerate your organs in the next 10 years, you could do it from your own cell line.
which has a lot of advantages over someone else's stem cells. And I can also create a cardiac cell called organ on a chip technology and test that cardiac cell against drug response. So today that's available. It takes about six months to create that.
Mizter Rad (15:46)
Sorry, this like an organoid kind of thing?
Dr. Hannah-Schmouni (15:52)
It is, yeah, it's an organoid. Today I have the ability to do it through a brilliant company called Curious AI and they have that commercially available. We commercialize it through our clinical infrastructure here in Dubai and elsewhere. We call this program personalized plus and
Mizter Rad (16:13)
that
work? Just give me give me give me more details there. Like what do you mean with having an organoid that is related to your heart? Well, can you repeat that?
Dr. Hannah-Schmouni (16:24)
Yeah,
yeah, sure. So once I create your own stem cells and use pluripotent stem cells, I can then differentiate them into cardiac cells. So in a chip, in a jar, and then I can test those cells for drug responses. So I could tell you what you're allergic to and what reactions you'll get to certain drugs. So that's personalized medicine, right? And imagine where that future will take us beyond today.
Right, so I have the ability to do it today, but imagine in five years, I can create personalization across multi-systems and multi-cells in the body. And I can also create your own skin care products through these cells because the juice of the cell creates a lot of growth factors and other opportunities for you to create products that will help regenerate.
your organs, especially if you've got non-surgical orthopedic related diseases like tendon issues and injuries. And so the future is definitely personalized. The future is definitely what we call N is one. And there's going to be designer drugs out there. know, AI and AI agents and AI algorithms are going to custom and personalize products and services for you. For example, in the event of a pandemic,
We don't need a guess game where everyone's gonna get the same vaccine for a particular virus. It's going to be personalized for you based on your big data input. And so the future is going to look like your biology being deciphered into a digital twin that sits in your pocket.
that talks to you at all times, that analyzes your big data from your home to your genome to your blood work. And then it will constantly create personalized insights and it will surveil you and it knows your history much better than anyone else. And it can go to medical appointments on your behalf and really personalized and customized based on big data, including exposures, environmental exposures. So where can we be in 50 years? boy.
You know, I'm excited about the possibility of unlocking human potential through technology. So I predict a future where all of us are going to have a chip, right, like Neuralink chip that's going to optimize and unlock so many areas of our brain that are yet to be discovered. And imagine what we can do, right, when that happens. We will also get to a point with regenerative therapies where we can regenerate organs.
Of course, with CRISPR-like interventions, you could get rid of bad genetic traits that you've inherited and replace it with advantageous traits, whether it's for the purpose of sports or other related traits. And I see also a future where it's very predictive, where you will truly become the best hedge fund manager for your health. And you can potentially escape death.
you know, and this is something they call longevity escape velocity, right? Where you're going to live to as long as you can and not die from something stupid. So in other words, I want to give a signal of hope and optimism that we're moving in the right direction for extending health span. The healthy years lived on earth, and this is not magic and voodoo science. You know, we see it. you know, it's, you know, rejuvenation is real.
You know aging is a choice. We can decelerate aging. We can create healthy optimized humans Today and in the near future. We're just going to double down on this potential So I'm very bullish on where where humanity is going to land in the near and far future
Mizter Rad (20:25)
Hmm. Interesting look I've been hearing and I'm sure you've been hearing a lot about quantum computing lately and its potential impact on many fields, including medicine, of course, and as far as I understand from from this conversation and all the conversations I've had in the show, we already starting to personalize these treatments based on like you were saying genetics. But I wonder when this quantum computing computers.
I wonder what they could do. I mean, they could potentially model the human body at an atomic level, something that is almost impossible right now with the current technology. How do you think this ultra precise understanding would change medicine beyond what we are doing now already? Like, could we go from today's somewhat personalized approach to treatments designed for the exact sort of molecular
structure of your specific cells, let's say.
Dr. Hannah-Schmouni (21:28)
Yeah, absolutely. think that quantum computing, quantum annealing technology through companies like D-Wave, which are publicly traded and have a commercially available product, can help optimize AI accuracy and output. So today we could use quantum computing for optimization, which then leads to a better output for whether it's drug discovery or anything that's AI being used for.
Down the road, mean, the potential for quantum is massive for drug discovery and for human optimization. And quantum biology is another interesting field and we use it. We use grounding and other quantum biology based products and services to optimize humans, to decrease inflammation, to promote healing. It's a very interesting field to look into. And the body is a quantum machine.
in the first place. So if you know how to hack it and to optimize it, you'll get a better output. So I'm bullish on the intersection between quantum and AI today for optimization. And I can't predict what's going to happen in the future with quantum. But if it goes in the right hands, we're going to see great things. If it goes in the wrong hands, like what I said earlier, there are good actors and bad actors with everything. It can lead to massive population wipeouts. So again, I'm an optimist. What I'm seeing is the
potential to optimize humans with what we have today and what we're going to have in the future. And that's going to lead to a healthier population, healthier economy down the road. So we're going through expansion, right? And that's not going to stop anytime soon.
Mizter Rad (23:12)
Hmm. That's interesting. It's interesting that you touch quantum biology because I wanted to get into that topic a little bit because it's very related to what we're talking about now. And I want to try something a bit mind bending here. We know hormones and maybe you correct me if I'm wrong and I'm going to make this very simplistic for the people in general to understand that also for myself to be clear. We know hormones are made of amino acids.
which are made of atoms, which are made of subatomic particles, of course, that contain things like quarks. And that's about as far as we understand right now. Most medicine works at a chemical level, let's say, adding molecules to affect, for example, hormones. But I'm wondering about the deeper levels, like you were saying, standing on the ground. is the, you know, it's crazy to think that someday we might treat
health problems by influencing this fundamental particles and actually I talk about that topic of quantum biology with Dr Clarice Aiello. She's from UCLA and she's building really cool stuff in the sector of quantum biology, episode 37. Do you think that quantum medicine could actually at some point sort of manipulate the building blocks of matter to fix health issues at their most?
basic level, let's say, is this getting too sci-fi here?
Dr. Hannah-Schmouni (24:42)
Yeah, I'm a believer of quantum, anything quantum related, including quantum biology. Although in my traditional training as an internist, endocrinologist and clinical biochemical geneticist, I really never touched on the topic of quantum biology because traditional care educational models don't really describe those important cellular energetic processes as such. But when I left traditional care models and went
onto the wellness longevity ecosystem, I had the pleasure and privilege of building several longevity programs across different clinics and came across very important quantum biology related products that changed some of our clients' lives. So let's break it down because I think this is very important. It's an ascent industry. As you know, I think we're going to see a lot of research and products and services evolve in this field. But what is
quantum biology, right? So it's a field that explores how quantum mechanics influences our biological processes. And it includes like superposition, entanglement, tunneling, and it's across different species. For example, photosynthesis, is energy transfer within the light harvesting complexes of plants and bacteria is a quantum biology based process. Human body is a biochemical reaction.
of so many different pathways, right? And it requires raw material in to give you an output that that's all catalyzed by enzymes, right? So the enzymes use quantum tunneling to transfer electrons and protons. The mitochondria, the powerhouse cell uses the same sort of biochemical and quantum mechanics to generate energy. Even the sense of smell might rely on quantum vibrations rather than just
sort of the basic principles of molecules binding to nerves and creating signals, right? DL mutations also contribute to, and the spontaneous mutations that happens in the DNA that lead to disease might be a product of quantum biology-based mechanics. So what I'm trying to say is that while it requires further validation and studying, our body
the building blocks of our body and the building blocks of our chemical reactions are all quantum biology based reactions. And if we optimize these reactions with quantum biology based interventions, such as grounding, which is putting your feet on the ground, right? And allowing the transfer of energy between the ground and your body may help preset some of these and optimize some of these pathways. If you use a pulse electromagnetic field, MAT,
that will help transfer energy within your body that may help optimize your quantum biology processes and so on and so forth.
Mizter Rad (27:43)
Can we measure, like if I stand on the ground today for half an hour, do we have the ability to measure the impact on that already?
Dr. Hannah-Schmouni (27:53)
So there are sensors that can show you how your body changes to certain grounding techniques. Okay. But we don't know. And of course you could study your cells under the microscope pre and post grounding to see how they bud with one another. It's quite an interesting experiment. But the bigger question is what changes short and long term will that have on your health? Right.
know, correlation, causality, that's going to be very hard to study. And the reason behind that is because there are so many, what we call covariates, right? So many things that can influence the relationship between the intervention and the outcome. And it's very hard to design very good studies that can give you a final sort of outcome.
on the intervention, particularly pertaining to the wellness-based interventions. But you know, I practice grounding every day and I've seen a positive effect on my body. At a minimum, you know, it helps me with being grounded as a person and helps me focus. I encourage everyone to at least, and especially my colleagues in the traditional care models, to listen to what's happening outside of the traditional care models.
Some of these practices, by the way, are quite ancient, right? Right. Yeah. Yeah. my, I guess my message is that let's be open. Let's explore other fields of medicine. Let's empower our clients and patients to think outside the box. Let's offer them hope outside of the traditional care models. That's what I do as a practicing
endocrinologist and longevity physician in our clinic here at Zoime in Dubai. But that's what I teach as a faculty at the Geneva College of Longevity Sciences is to be open minded because because you know, we want to we want to at the end of the day, create good value for our clients.
Mizter Rad (30:08)
Right, you actually, Dr. Schmouni, can you walk me through what happens when someone comes to your praxis with, let's say, chronic fatigue or brain fog that several doctors haven't been able to solve maybe and this person comes to you and says, look, this is my problem. What's your process for diagnosis and treatment that differs maybe from that conventional doctor?
Dr. Hannah-Schmouni (30:34)
Yeah, so I'm the co-founder and group CEO of the NU. We are an operating system that analyzes multi-omic big data to create digital twins and personalized insights. And we've got our own clinic in Dubai called Zoey and Me operated by our operating system. A typical client journey includes them coming in, getting their salivary tests for epigenome genome, their stool tests for microbiome,
100 plus blood biomarkers, including mold testing, hormones, vitamins.
Mizter Rad (31:10)
mold testing how do you do that
Dr. Hannah-Schmouni (31:13)
Yeah, so we do that through an antigen test in the blood and urine-based test as well. one in five people have an abnormal mold test. And mold can lead to systemic signs and symptoms including brain fogginess. know, if we can't find a mold to be the cause of the symptoms, we look at other markers, for example, environmental toxins. So we do an environmental toxin test including
endocrine disrupting chemicals. As you know, there are over 80,000 chemicals in our environment, including microblastics, phthalates, and so on. So we have the ability of measuring about 50 of those 80,000, believe it or not, either in urine or blood. Yeah. And so, you know, we've seen improvements when it comes to sort of these non-specific signs and symptoms like brain fog with mold-related treatments, with...
Mizter Rad (31:55)
That's a lot of chemicals,
Dr. Hannah-Schmouni (32:10)
changing the oil in the blood, which is called plasma exchange, that gets sort of filters out all the inflammatory markers and toxins and clearly environmental toxins and mold. And so there's a few, and of course mental health. So everyone that goes through a program sees a psychologist and brain fogginess can be a manifestation of mental health disease, including depression, undiagnosed depression. So.
Mizter Rad (32:38)
So do they, let me jump in right there, because you said they have to come in the Dubai premises. Is that something that you could do remote at some point as well?
Dr. Hannah-Schmouni (32:49)
Yeah, so we are launching a direct to consumer virtual care program so we can provide accessibility to our program. our business model as a deep tech company is to license our operating systems to other clinics and share with them our protocols so we could replicate what we've built to so many other different platforms. So our mission
Mizter Rad (33:03)
I see.
Dr. Hannah-Schmouni (33:13)
and vision is to scale longevity through operating systems so we can create a more cost effective, scalable, multi-omic digital twin technology so businesses can provide a more holistic, integrative care through our big data analytic platforms.
Mizter Rad (33:30)
When you say multi-omic, what do you mean with that?
Dr. Hannah-Schmouni (33:32)
Yeah. Multi means many. And omic is, is big data. So I take your big data from your genetic, epigenetic blood from your wearable. So everyone that comes through our clinics gets a wearable that's integrated into our app. And we integrate with third party wearables, including whoop and aura. I take your big data from imaging, like a DEXA scan and MRI. And I also take data from the questionnaires that I ask you. And in the future, we're going to take big data from your smart home technology.
such as your air purifiers, your smart waters, your fridge, your bed sensors, your smart mirrors. So these different layers of data are called Omics. And we need that to train on models to create your digital twin, which is a digital replica of your complex biology. And that's in your pocket through our app and that connects to your data and to your wearables. And it connects to me in the clinic or to our licensees that license our operating system.
And the idea is to give you access to your digital biology so you can get personalized insights. Because today with AI and bioinformatics and technology, we can really compare you to an enabling database and reference population and tell you how you're doing. And we also have proprietary age clocks, which are models to tell us
how well are you and your different organ systems, including your DNA, compared to a reference population? And we can monitor these models over time to see if you're moving in the right direction or the wrong direction. So, you know, to summarize it, it's a hedge fund for health. We create the operating system infrastructure, so we allow other businesses to hedge and to create more value and health opportunities for their clients.
Mizter Rad (35:21)
That's very interesting. So would you say that with your work that you're doing today with, the kind of advancements that you're seeing today, and also with your work with hormones every day, we know that this traumatic, that this is changing dramatically every day. And in the case of hormone health or health in general, it changes of course, as we age based on what you've seen so far and what we're discovering right now, how might.
hormonal treatments, for example, just to be specific, evolved by, oh, let's say in the next five decades, for instance, do you think we see a future where a say 75 year old woman has the estrogen levels of a 30 year old self maintaining, for example, strong bones, sharp cognition, a beautiful skin, or where an 80 old man
maintains the testosterone levels that support muscle mass, energy, libido, similar to when he was 20, for example. What would that mean for how we age, look, and function as a human species, for example?
Dr. Hannah-Schmouni (36:34)
Yeah, what a great question, right? Which goes back to the idea of creating personalized interventions for everyone so they could live longer, healthier with the same sort of system they had when they were younger and say in their twenties. Now, why do we decline? Why do we decline with age? And I think there's an evolutionary mismatch between what we inherited from evolution and what we need today.
And we see this in our 30s, we start to have a decline of our hormones by about 1 % per year, say testosterone, our muscles start declining. After 50, we go through a process of anabolic resistance whereby our muscles don't have the same ability to build and be healthier as its younger self. And the question is why?
Is it because of a genetic mismatch? Is it because of an environmental mismatch? Is it because we're constantly exposed to environmental toxins and that gives us the disadvantage and helps decelerate our processes and speed up aging? Is it because of everything else we're exposed to in the economy, such as stress and relationship issues and psychosocial problems? We don't know. It's definitely a multitude of different factors that's leading
our overall decline. And we see this with sperm counts. Over the past 60 years, our fertility rates and sperm counts have significantly dropped. We see testosterone levels in men have significantly dropped over the past decades. We see higher rates of cancer, especially in younger age. We see people are becoming more more frail as they age and so on. the opportunity is then to identify these issues that are causing the rapid decline.
of let's call it health span and then to try to reverse that trajectory. So how can we reverse that trajectory? Well today we can easily reverse it with replacement therapy. So we can easily reverse it with hormone replacement therapy. Like if someone doesn't have an optimal testosterone, start them on TRT. If a female is in the perimenopausal stage and has no testosterone and sort of a very erratic estrogen and progestin levels, then start them on hormone replacement therapy earlier.
especially testosterone in females. Now, where will the future be? Right? So to answer your question, could we see, could we get to a future where we can delay menopause and andropause in males? The short answer is yes, but no one has done it yet. No one has been able to stop the ovaries from aging and turning into sort of menopausal ovaries by 51 years of age.
There are a lot of attempts, but no one has done it successfully yet. Will we get there in 30 years? Maybe. But here's where I think the biggest potential opportunity is, it's in gene therapy. So we know today that we could introduce different genetic material into your cells so they could produce products and services that you once did when you were much younger. So then could we...
create gene therapies for ovaries and gene therapies for testosterone and gene therapies for so many other products so we could stay younger and always produce the same amounts that our younger cells did. There are companies that are testing these interesting theories right now. I know of at least one company that's commercializing gene therapy products for the hope of revitalizing our hormones.
but I would love to see more evidence. But I think in short, what I'm trying to suggest here is that we will have the ability to biohack our hormonal and non-hormonal system and bring back our youth in the very short period of time that we have.
Mizter Rad (40:36)
So would you say that for my listeners that are building legacy companies for the next five decades, would you say that would be an interesting problem to solve to build a company that sort of hides that wave and tries to build therapies that are safe, that are reliable, that are accessible?
Dr. Hannah-Schmouni (40:54)
I think that everyone should consider going into the wellness and longevity economy, which is projected to be 6 % of global GDP by 2030.
Mizter Rad (41:02)
When
you say wellness, sorry to interrupt there, but when you say wellness, there is already a sort of an image painted in the brains of people when people hear, at least in Europe where I live, when people hear wellness, they think about the spa and the sauna. And that's it. It's kind of like that's the roof. That's it. Well, what do you mean with wellness?
Dr. Hannah-Schmouni (41:22)
Yeah, I mean, the spas and the saunas and the cold plunges and the supplements and the gyms are all part of the wellness economy, but there's more. So any consumer product, whether it's testing products, whether it's at home services, whether it's biotechnology or whatever it is that's creating consumer-faced products, whether it's an infrastructure play like software for consumers, whether it's beauty, industry.
cosmetics, you know, you name it. And then let's go into the other segment of wellness, which I'm very passionate about, which is the longevity wellness real estate market. So now real estate developers are thinking about ways of incorporating wellness related products and services, including building wellness focused gyms, longevity focused gyms, longevity clinics, smart home technologies, at home services, in the master plan real estate developers. And a perfect example is Tony Robbins,
He just recently announced Wellness Real Estate Initiative, that's multi-billion dollar in value, and he's going to incorporate a lot of these longevity and wellness related products and services inside these mega master developments. So yeah, the wellness economy is massive, it's growing to meet consumer demands, and a lot of people can do a lot of things in the wellness economy. On the medical side,
we're seeing also transformational shift from traditional models to more of the wellness longevity model. So there's a big opportunity there, whether it's on the diagnostics or the treatments or the repurposing of drugs or the sort of gen AI models of identifying drugs and really disrupting the traditional way of doing business in the traditional care model. In our instance, for example, we chose to be an infrastructure play, an operating system play because we see
growth and demand in this industry. So what would everyone need? They're going to need roads to be paved, houses to be built, electricities to be connected in this new economy. So this is where we come in as a deep tech company. We've built an operating system to upgrade the infrastructure, the technology infrastructure needed as this economy grows. so there are so many other examples of infrastructure that is needed in this economy.
And I encourage entrepreneurs to consider it because to consider at least understanding the economy, understanding how to create value in this economy and then based on it, build successful businesses.
Mizter Rad (43:52)
Exciting. Dr. Fadi, I sometimes think of two competing trends and I want to poke your brain on this. On the one hand, humans becoming more trans humans with implants and generic. I actually have an implant here on my humerus and on my finger. They're not connected to the Internet, but they could. Genetic modifications, AI integrations, all the beautiful tech that we talked about before.
quantum biology, quantum medicine, et cetera. But on the other hand, you find people seeking more natural holistic approaches to health. Which trend do you see winning? Do you think they will merge at some point? Do you think they're merging anyway? Do you think they will stay separate? And some people will be here. Some people that have money will be here. Some people that don't have money will be here. How do you think this will play out?
Dr. Hannah-Schmouni (44:43)
Yeah, I'll give you another analogy. think it's let's talk about safe and clean water. We've had water for so long and yet most of populations on earth don't have access to clean water. Right. And only the privileged, right, that live in developed and some developing countries have access to clean water. And we're going to see the same trend with technology. You know, as technology evolves,
It's going to be used by the fortunate few that have access, including capital and of course access to markets where you could purchase these technologies. humans will continue to evolve in sort of different segments, right? The segment that don't have access to the basic necessities of life and then the segments that will always have access to the latest in life.
So yeah, I don't think this is gonna change unless we have more people like Elon Musk that will build technologies that would disrupt industry significantly and bring down the cost of technology for the masses like Starlink, for example. But again, I'm a very optimist and I think that we're going to see
a future of abundance that will help propel humans to an extraordinary stage of optimization, growth, and opportunity to continue to expand this beautiful world we live in.
Mizter Rad (46:25)
That's beautiful. That's beautiful. Look, before we wrap up, I'm curious as someone who knows so much about optimal health and and optimal living, what are your daily health routines? What do they look like? What's the one thing you never skip even on your busiest days or even when you're traveling? Because I find that super hard, actually. When I travel, it's hard to keep up with my routines. But what's your
experience in that.
Dr. Hannah-Schmouni (46:56)
Yeah, so I'm going to tell you everything I do personally and it doesn't have to, and it's after years of research and experience. But, you know, one of the things I do when I wake up in the morning is I take my 10 grams of creatine and a shot of peptides. Before going to the gym, I do personal training six days a week, focusing on lowering my body fat, building muscle, which is the organ of longevity and improving my overall fitness.
And I then go for a half an hour walk. So it's my me time. This is where I do grounding and breath work. And then I head to work and at work. So I start my day with a very high note. then I have coffee. I have eggs and coffee. I optimize my because I'm building muscle, I optimize my protein intake. I love coffee.
I then take some supplements throughout the day focusing on mitochondrial health like Coenzyme Q10. And then, you know, I work and because of how busy work is, that tends to put me into a fasting state for hours. I then have another sort of protein rich meal, at least four hours before going to bed. Work keeps me very stimulated. I'm around people all the time. So there's that sense of community around me. I love productivity.
and I avoid negativity. So on weekends, you know, I spend Sundays with my wife. This is our sort of time off from the world. And at night I try to sleep regularly as much as I can. And I use my wearable technology to sort of give me a rough idea of how I'm doing in terms of, you know, HRV and sleep scores and output. And I do my blood work every three to six months. I do a
full body MRI every three years. then, you know, what I want to do in the future is have a sort of a life coach, someone that can continue to train me to reach greater heights.
Mizter Rad (49:04)
Maybe
that could be AI as well.
Dr. Hannah-Schmouni (49:06)
Yeah, it won't be the same though. I tried, I have a clone. I have a clone that I, and I used Delphi.ai, which is an incredible company, built my own clone, but it's not a sticky product. I still love human interaction and I don't think we're gonna, AI is gonna replace the human interaction anytime soon.
Mizter Rad (49:25)
Yeah, I hope not. I hope not. think human interaction is beautiful. It's irreplaceable. Well, Dr. Smoni, Fadi, Shukran. Shukran. It's been a real pleasure talking with you. Thank you. care, my friend. Until next time, beautiful humans, stay curious, question everything, and maybe, just maybe, start treating your body like the complex, unique system it is.
Dr. Hannah-Schmouni (49:31)
Yeah, yeah, absolutely.
Thank you. Take care.
Mizter Rad (49:52)
One that deserves personalized care, not just standardized solutions. Hasta la vista! Ciao Fabi!
Dr. Hannah-Schmouni (49:58)
Ciao ciao.
Here at the Mizter Rad Show, we provide first-hand information straight from the original source of knowledge. The personal opinions of our guests don't necessarily reflect those of Mizter Rad. This show is brought to you by The Rad House, an unbiased, transparent, agenda-less, independent media house. Our theme music is written and produced by Marco Mello.